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Nov 4, 2022Laboratorio di Biologia Cellulare e Molecolare Applicata a Patologie del Neurosviluppo
Part of the projects are focused on the study of astrocytes and particularly astrocyte-neuron communication in Rett syndrome, considering the importance of both cell- and non cell-autonomous mechanisms in the disease. Specifically, we are interest to study the molecular mechanism... |
Nov 4, 2022
The laboratory's research is focused on the study of pathologies associated with MECP2 and CDKL5 with both a basic and a translational approach. In general, the projects developed in the lab aim to identify molecular and cellular defects that can become a logical target for new p... |
Jul 18, 2022
Duchenne Muscular Dystrophy (DMD) is a complex disorder characterized by the lack of dystrophin, a protein fundamental to maintaining muscle integrity during contraction. While remarkable progress has been made in genetic approaches to restore dystrophin, or its function, targeti... |
Jan 5, 2022 - ncRNAging
Battaglia, Cristina, 2022, "Investigation on ncRNA in senescence in senescence cellular models", https://doi.org/10.13130/RD_UNIMI/OXXJ1N, UNIMI Dataverse, V1
Cellular senescence is a hallmark of aging and is the result of a variety of stresses, such as telomere attrition, DNA damage and mitochondrial dysfunction. Moreover, senescent cells display a typical secretory phenotype, which involves the secretion of several inflammatory facto... |