Il Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, nato dall’incontro tra interessi e competenze nell’ambito sia delle scienze molecolari e cellulari di base e applicate alla medicina, sia delle scienze cliniche, individua nella ricerca e nella didattica due aspetti che vogliono essere il più possibile integrati. Nel Dipartimento confluiscono professori e ricercatori afferenti a settori scientifico-disciplinari attinenti alla ricerca di base in ambito biofisico, molecolare e cellulare, alla ricerca applicata alla medicina, alla diagnostica, e alla medicina clinica e chirurgica con l’intento di promuovere e coordinare attività di ricerca traslazionali e multidisciplinari.
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11 to 17 of 17 Results
RTT_Astroctyes_Dataverse(University of Milan)
Nov 4, 2022Laboratorio di Biologia Cellulare e Molecolare Applicata a Patologie del Neurosviluppo
Part of the projects are focused on the study of astrocytes and particularly astrocyte-neuron communication in Rett syndrome, considering the importance of both cell- and non cell-autonomous mechanisms in the disease. Specifically, we are interest to study the molecular mechanism...
Nov 4, 2022
The laboratory's research is focused on the study of pathologies associated with MECP2 and CDKL5 with both a basic and a translational approach. In general, the projects developed in the lab aim to identify molecular and cellular defects that can become a logical target for new p...
Clara De Palma Dataverse(University of Milan)
Jul 18, 2022
Duchenne Muscular Dystrophy (DMD) is a complex disorder characterized by the lack of dystrophin, a protein fundamental to maintaining muscle integrity during contraction. While remarkable progress has been made in genetic approaches to restore dystrophin, or its function, targeti...
Jan 5, 2022 - ncRNAging
Battaglia, Cristina, 2022, "Investigation on ncRNA in senescence in senescence cellular models", https://doi.org/10.13130/RD_UNIMI/OXXJ1N, UNIMI Dataverse, V1
Cellular senescence is a hallmark of aging and is the result of a variety of stresses, such as telomere attrition, DNA damage and mitochondrial dysfunction. Moreover, senescent cells display a typical secretory phenotype, which involves the secretion of several inflammatory facto...
ncRNAging(University of Milan)
Dec 15, 2021Cristina Battaglia Dataverse
Aging is described as a gradual decline in cellular functions, eventually leading to tissue dysfunctions. Thus age is considered a risk factor for several pathologies, e.g. cardiovascular and neurodegenerative diseases. The prevention of age-related diseases and the promotion of...
Cristina Battaglia Dataverse(Università degli Studi di Milano)
Dec 15, 2021
SEED2020_IMPATTO(University of Milan)
Dec 14, 2021
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