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RTT_Astroctyes_Dataverse(University of Milan)
Nov 4, 2022Laboratorio di Biologia Cellulare e Molecolare Applicata a Patologie del Neurosviluppo
Part of the projects are focused on the study of astrocytes and particularly astrocyte-neuron communication in Rett syndrome, considering the importance of both cell- and non cell-autonomous mechanisms in the disease. Specifically, we are interest to study the molecular mechanism...
Nov 4, 2022
The laboratory's research is focused on the study of pathologies associated with MECP2 and CDKL5 with both a basic and a translational approach. In general, the projects developed in the lab aim to identify molecular and cellular defects that can become a logical target for new p...
Clara De Palma Dataverse(University of Milan)
Jul 18, 2022
Duchenne Muscular Dystrophy (DMD) is a complex disorder characterized by the lack of dystrophin, a protein fundamental to maintaining muscle integrity during contraction. While remarkable progress has been made in genetic approaches to restore dystrophin, or its function, targeti...
Jan 5, 2022 - ncRNAging
Battaglia, Cristina, 2022, "Investigation on ncRNA in senescence in senescence cellular models", https://doi.org/10.13130/RD_UNIMI/OXXJ1N, UNIMI Dataverse, V1
Cellular senescence is a hallmark of aging and is the result of a variety of stresses, such as telomere attrition, DNA damage and mitochondrial dysfunction. Moreover, senescent cells display a typical secretory phenotype, which involves the secretion of several inflammatory facto...
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